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Large-scale exome sequence analysis identifies sex- and age-specific determinants of obesity
Obesity contributes substantially to the global burden of disease and has a significant heritable component. Recent large-scale exome sequencing studies identified several genes in which rare, protein-coding variants have large effects on adult body mass index (BMI). Here we extended such work by pe...
Autores principales: | Kaisinger, Lena R., Kentistou, Katherine A., Stankovic, Stasa, Gardner, Eugene J., Day, Felix R., Zhao, Yajie, Mörseburg, Alexander, Carnie, Christopher J., Zagnoli-Vieira, Guido, Puddu, Fabio, Jackson, Stephen P., O’Rahilly, Stephen, Farooqi, I. Sadaf, Dearden, Laura, Pantaleão, Lucas C., Ozanne, Susan E., Ong, Ken K., Perry, John R.B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435378/ https://www.ncbi.nlm.nih.gov/pubmed/37601970 http://dx.doi.org/10.1016/j.xgen.2023.100362 |
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