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Accurate microRNA annotation of animal genomes using trained covariance models of curated microRNA complements in MirMachine

The annotation of microRNAs depends on the availability of transcriptomics data and expert knowledge. This has led to a gap between the availability of novel genomes and high-quality microRNA complements. Using >16,000 microRNAs from the manually curated microRNA gene database MirGeneDB, we gener...

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Detalles Bibliográficos
Autores principales: Umu, Sinan Uğur, Paynter, Vanessa M., Trondsen, Håvard, Buschmann, Tilo, Rounge, Trine B., Peterson, Kevin J., Fromm, Bastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435380/
https://www.ncbi.nlm.nih.gov/pubmed/37601971
http://dx.doi.org/10.1016/j.xgen.2023.100348