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Excessive vincristine exposure in a child being treated for acute lymphoblastic leukaemia with underlying Dubin–Johnson syndrome: a case report

BACKGROUND: Dubin–Johnson syndrome is a rare benign autosomal recessive condition that causes an isolated increase of conjugated bilirubin in the serum. Impaired biliary excretion is due to mutation in the multiple drug-resistance protein 2 gene (MRP2). CASE PRESENTATION: We describe the case of a 4...

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Detalles Bibliográficos
Autores principales: Barnett, Shelby, Nyein, Aye Chan, Galler, Martin, Jamieson, David, Davies, Michelle, Connor, Philip, Veal, Gareth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435398/
https://www.ncbi.nlm.nih.gov/pubmed/37452859
http://dx.doi.org/10.1007/s00280-023-04565-0