A RAD51–ADP double filament structure unveils the mechanism of filament dynamics in homologous recombination

ATP-dependent RAD51 recombinases play an essential role in eukaryotic homologous recombination by catalyzing a four-step process: 1) formation of a RAD51 single-filament assembly on ssDNA in the presence of ATP, 2) complementary DNA strand-exchange, 3) ATP hydrolysis transforming the RAD51 filament...

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Detalles Bibliográficos
Autores principales: Luo, Shih-Chi, Yeh, Min-Chi, Lien, Yu-Hsiang, Yeh, Hsin-Yi, Siao, Huei-Lun, Tu, I-Ping, Chi, Peter, Ho, Meng-Chiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435448/
https://www.ncbi.nlm.nih.gov/pubmed/37591853
http://dx.doi.org/10.1038/s41467-023-40672-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435448/
https://www.ncbi.nlm.nih.gov/pubmed/37591853
http://dx.doi.org/10.1038/s41467-023-40672-5

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