MenT nucleotidyltransferase toxins extend tRNA acceptor stems and can be inhibited by asymmetrical antitoxin binding

Mycobacterium tuberculosis, the bacterium responsible for human tuberculosis, has a genome encoding a remarkably high number of toxin-antitoxin systems of largely unknown function. We have recently shown that the M. tuberculosis genome encodes four of a widespread, MenAT family of nucleotidyltransfe...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Xibing, Usher, Ben, Gutierrez, Claude, Barriot, Roland, Arrowsmith, Tom J., Han, Xue, Redder, Peter, Neyrolles, Olivier, Blower, Tim R., Genevaux, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435456/
https://www.ncbi.nlm.nih.gov/pubmed/37591829
http://dx.doi.org/10.1038/s41467-023-40264-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435456/
https://www.ncbi.nlm.nih.gov/pubmed/37591829
http://dx.doi.org/10.1038/s41467-023-40264-3

Ejemplares similares