Cell-specific and shared regulatory elements control a multigene locus active in mammary and salivary glands

Regulation of high-density loci harboring genes with different cell-specificities remains a puzzle. Here we investigate a locus that evolved through gene duplication and contains eight genes and 20 candidate regulatory elements, including one super-enhancer. Casein genes (Csn1s1, Csn2, Csn1s2a, Csn1...

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Detalles Bibliográficos
Autores principales: Lee, Hye Kyung, Willi, Michaela, Liu, Chengyu, Hennighausen, Lothar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435465/
https://www.ncbi.nlm.nih.gov/pubmed/37591874
http://dx.doi.org/10.1038/s41467-023-40712-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435465/
https://www.ncbi.nlm.nih.gov/pubmed/37591874
http://dx.doi.org/10.1038/s41467-023-40712-0

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