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Cell-specific and shared regulatory elements control a multigene locus active in mammary and salivary glands
Regulation of high-density loci harboring genes with different cell-specificities remains a puzzle. Here we investigate a locus that evolved through gene duplication and contains eight genes and 20 candidate regulatory elements, including one super-enhancer. Casein genes (Csn1s1, Csn2, Csn1s2a, Csn1...
Autores principales: | Lee, Hye Kyung, Willi, Michaela, Liu, Chengyu, Hennighausen, Lothar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435465/ https://www.ncbi.nlm.nih.gov/pubmed/37591874 http://dx.doi.org/10.1038/s41467-023-40712-0 |
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