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High-sensitive nascent transcript sequencing reveals BRD4-specific control of widespread enhancer and target gene transcription
Gene transcription by RNA polymerase II (Pol II) is under control of promoters and distal regulatory elements known as enhancers. Enhancers are themselves transcribed by Pol II correlating with their activity. How enhancer transcription is regulated and coordinated with transcription at target genes...
Autores principales: | Bressin, Annkatrin, Jasnovidova, Olga, Arnold, Mirjam, Altendorfer, Elisabeth, Trajkovski, Filip, Kratz, Thomas A., Handzlik, Joanna E., Hnisz, Denes, Mayer, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435483/ https://www.ncbi.nlm.nih.gov/pubmed/37591883 http://dx.doi.org/10.1038/s41467-023-40633-y |
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