LINE-1 regulates cortical development by acting as long non-coding RNAs

Long Interspersed Nuclear Elements-1s (L1s) are transposable elements that constitute most of the genome’s transcriptional output yet have still largely unknown functions. Here we show that L1s are required for proper mouse brain corticogenesis operating as regulatory long non-coding RNAs. They cont...

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Detalles Bibliográficos
Autores principales: Mangoni, Damiano, Simi, Alessandro, Lau, Pierre, Armaos, Alexandros, Ansaloni, Federico, Codino, Azzurra, Damiani, Devid, Floreani, Lavinia, Di Carlo, Valerio, Vozzi, Diego, Persichetti, Francesca, Santoro, Claudio, Pandolfini, Luca, Tartaglia, Gian Gaetano, Sanges, Remo, Gustincich, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435495/
https://www.ncbi.nlm.nih.gov/pubmed/37591988
http://dx.doi.org/10.1038/s41467-023-40743-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435495/
https://www.ncbi.nlm.nih.gov/pubmed/37591988
http://dx.doi.org/10.1038/s41467-023-40743-7

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