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A deep learning method for replicate-based analysis of chromosome conformation contacts using Siamese neural networks
The organisation of the genome in nuclear space is an important frontier of biology. Chromosome conformation capture methods such as Hi-C and Micro-C produce genome-wide chromatin contact maps that provide rich data containing quantitative and qualitative information about genome architecture. Most...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435498/ https://www.ncbi.nlm.nih.gov/pubmed/37591842 http://dx.doi.org/10.1038/s41467-023-40547-9 |