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A deep learning method for replicate-based analysis of chromosome conformation contacts using Siamese neural networks

The organisation of the genome in nuclear space is an important frontier of biology. Chromosome conformation capture methods such as Hi-C and Micro-C produce genome-wide chromatin contact maps that provide rich data containing quantitative and qualitative information about genome architecture. Most...

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Detalles Bibliográficos
Autores principales: Al-jibury, Ediem, King, James W. D., Guo, Ya, Lenhard, Boris, Fisher, Amanda G., Merkenschlager, Matthias, Rueckert, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435498/
https://www.ncbi.nlm.nih.gov/pubmed/37591842
http://dx.doi.org/10.1038/s41467-023-40547-9