The identification of genes associated T-cell exhaustion and construction of prognostic signature to predict immunotherapy response in lung adenocarcinoma

T-cell exhaustion (Tex) is considered to be a reason for immunotherapy resistance and poor prognosis in lung adenocarcinoma. Therefore, we used weighted correlation network analysis to identify Tex-related genes in the cancer genome atlas (TCGA). Unsupervised clustering approach based on Tex-related...

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Detalles Bibliográficos
Autores principales: Wu, Yahua, Du, Bin, Lin, Mingqiang, Ji, Xiaohui, Lv, Chengliu, Lai, Jinhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435542/
https://www.ncbi.nlm.nih.gov/pubmed/37592010
http://dx.doi.org/10.1038/s41598-023-40662-z