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Cas13d-mediated multiplex RNA targeting confers a broad-spectrum resistance against RNA viruses in potato

CRISPR-Cas systems endow the bacterial and archaeal species with adaptive immune mechanisms to fend off invading phages and foreign plasmids. The class 2 type VI CRISPR/Cas effector Cas13d has been harnessed to confer the protection against RNA viruses in diverse eukaryotic species. However a vast n...

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Detalles Bibliográficos
Autores principales: Zhan, Xiaohui, Liu, Wenting, Nie, Bihua, Zhang, Fengjuan, Zhang, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435558/
https://www.ncbi.nlm.nih.gov/pubmed/37591976
http://dx.doi.org/10.1038/s42003-023-05205-2