Cargando…
Diabetes impairs fracture healing through Foxo1 mediated disruption of ciliogenesis
Foxo1 upregulation is linked to defective fracture healing under diabetic conditions. Previous studies demonstrated that diabetes upregulates Foxo1 expression and activation and diabetes impairs ciliogenesis resulting in defective fracture repair. However, the mechanism by which diabetes causes cili...
Autores principales: | Chinipardaz, Zahra, Yuan, Gongsheng, Liu, Min, Graves, Dana T., Yang, Shuying |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435563/ https://www.ncbi.nlm.nih.gov/pubmed/37591875 http://dx.doi.org/10.1038/s41420-023-01562-3 |
Ejemplares similares
-
FOXO 1 deletion in chondrocytes rescues diabetes-impaired fracture healing by restoring angiogenesis and reducing apoptosis
por: Alharbi, Mohammed A., et al.
Publicado: (2023) -
FOXO1 Deletion Reverses the Effect of Diabetic-Induced Impaired Fracture Healing
por: Alharbi, Mohammed A., et al.
Publicado: (2018) -
TNF-α Mediates Diabetes-Enhanced Chondrocyte Apoptosis During Fracture Healing and Stimulates Chondrocyte Apoptosis Through FOXO1
por: Kayal, Rayyan A, et al.
Publicado: (2010) -
FOXO1, TGF-β Regulation and Wound Healing
por: Hameedaldeen, Alhassan, et al.
Publicado: (2014) -
FOXO1 deletion in keratinocytes improves diabetic wound healing through MMP9 regulation
por: Zhang, Chenying, et al.
Publicado: (2017)