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Extensive breaking of genetic code degeneracy with non-canonical amino acids

Genetic code expansion (GCE) offers many exciting opportunities for the creation of synthetic organisms and for drug discovery methods that utilize in vitro translation. One type of GCE, sense codon reassignment (SCR), focuses on breaking the degeneracy of the 61 sense codons which encode for only 2...

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Detalles Bibliográficos
Autores principales: McFeely, Clinton A. L., Shakya, Bipasana, Makovsky, Chelsea A., Haney, Aidan K., Ashton Cropp, T., Hartman, Matthew C. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435567/
https://www.ncbi.nlm.nih.gov/pubmed/37591858
http://dx.doi.org/10.1038/s41467-023-40529-x