Elucidation of the low-expressing erythroid CR1 phenotype by bioinformatic mining of the GATA1-driven blood-group regulome

Genetic determinants underlying most human blood groups are now clarified but variation in expression levels remains largely unexplored. By developing a bioinformatics pipeline analyzing GATA1/Chromatin immunoprecipitation followed by sequencing (ChIP-seq) datasets, we identify 193 potential regulat...

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Detalles Bibliográficos
Autores principales: Wu, Ping Chun, Lee, Yan Quan, Möller, Mattias, Storry, Jill R., Olsson, Martin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435571/
https://www.ncbi.nlm.nih.gov/pubmed/37591894
http://dx.doi.org/10.1038/s41467-023-40708-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435571/
https://www.ncbi.nlm.nih.gov/pubmed/37591894
http://dx.doi.org/10.1038/s41467-023-40708-w

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