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Elucidation of the low-expressing erythroid CR1 phenotype by bioinformatic mining of the GATA1-driven blood-group regulome
Genetic determinants underlying most human blood groups are now clarified but variation in expression levels remains largely unexplored. By developing a bioinformatics pipeline analyzing GATA1/Chromatin immunoprecipitation followed by sequencing (ChIP-seq) datasets, we identify 193 potential regulat...
Autores principales: | Wu, Ping Chun, Lee, Yan Quan, Möller, Mattias, Storry, Jill R., Olsson, Martin L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435571/ https://www.ncbi.nlm.nih.gov/pubmed/37591894 http://dx.doi.org/10.1038/s41467-023-40708-w |
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