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Senescence program and its reprogramming in pancreatic premalignancy

Tumor is a representative of cell immortalization, while senescence irreversibly arrests cell proliferation. Although tumorigenesis and senescence seem contrary to each other, they have similar mechanisms in many aspects. Pancreatic ductal adenocarcinoma (PDA) is highly lethal disease, which occurs...

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Detalles Bibliográficos
Autores principales: Yang, Kailing, Li, Xiaojia, Xie, Keping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435572/
https://www.ncbi.nlm.nih.gov/pubmed/37591827
http://dx.doi.org/10.1038/s41419-023-06040-3