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Sterile liver injury induces a protective tissue-resident cDC1-ILC1 circuit through cDC1-intrinsic cGAS-STING-dependent IL-12 production

Tissue-resident immune cells are critical to the initiation and potentiation of inflammation. However, the tissue-protective cellular communication networks initiated by resident immunity during sterile inflammation are not well understood. Using single-cell transcriptomic analysis, we show the live...

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Detalles Bibliográficos
Autores principales: Hildreth, Andrew D., Padilla, Eddie T., Tafti, Rana Yakhshi, Legala, Akshara R., O’Sullivan, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435668/
https://www.ncbi.nlm.nih.gov/pubmed/36807146
http://dx.doi.org/10.1016/j.celrep.2023.112141