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Sterile liver injury induces a protective tissue-resident cDC1-ILC1 circuit through cDC1-intrinsic cGAS-STING-dependent IL-12 production
Tissue-resident immune cells are critical to the initiation and potentiation of inflammation. However, the tissue-protective cellular communication networks initiated by resident immunity during sterile inflammation are not well understood. Using single-cell transcriptomic analysis, we show the live...
Autores principales: | Hildreth, Andrew D., Padilla, Eddie T., Tafti, Rana Yakhshi, Legala, Akshara R., O’Sullivan, Timothy E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435668/ https://www.ncbi.nlm.nih.gov/pubmed/36807146 http://dx.doi.org/10.1016/j.celrep.2023.112141 |
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