Serum D‐2‐hydroxyglutarate and the ratio of D‐2HG/L‐2HG predict IDH mutation in acute myeloid leukemia

This study investigates whether serum D‐2HG (D‐2‐hydroxyglutarate) produced by the mutated isocitrate dehydrogenase (IDH) can predict IDH mutations in acute myeloid leukemia (AML) at diagnosis. D‐2HG and L‐2HG are measured by liquid chromatography‐tandem mass spectrometry. D‐2HG, total 2HG and the D...

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Detalles Bibliográficos
Autores principales: Zhang, Chelsea, Chu, Andrew, Boriack, Richard, Collins, Robert, Xu, Jing, Oliver, Dwight, Zheng, Ruifang, Rakheja, Dinesh, Chen, Weina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435681/
https://www.ncbi.nlm.nih.gov/pubmed/37601838
http://dx.doi.org/10.1002/jha2.723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435681/
https://www.ncbi.nlm.nih.gov/pubmed/37601838
http://dx.doi.org/10.1002/jha2.723

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