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Serum D‐2‐hydroxyglutarate and the ratio of D‐2HG/L‐2HG predict IDH mutation in acute myeloid leukemia
This study investigates whether serum D‐2HG (D‐2‐hydroxyglutarate) produced by the mutated isocitrate dehydrogenase (IDH) can predict IDH mutations in acute myeloid leukemia (AML) at diagnosis. D‐2HG and L‐2HG are measured by liquid chromatography‐tandem mass spectrometry. D‐2HG, total 2HG and the D...
Autores principales: | Zhang, Chelsea, Chu, Andrew, Boriack, Richard, Collins, Robert, Xu, Jing, Oliver, Dwight, Zheng, Ruifang, Rakheja, Dinesh, Chen, Weina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435681/ https://www.ncbi.nlm.nih.gov/pubmed/37601838 http://dx.doi.org/10.1002/jha2.723 |
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