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Therapeutic efficacy of the resorcylic acid lactone LL‐Z1640‐2 for adult T‐cell leukaemia/lymphoma

Adult T‐cell leukaemia/lymphoma (ATL) remains incurable. The NF‐κB and interferon regulatory factor 4 (IRF4) signalling pathways are among the critical survival pathways for the progression of ATL. TGF‐β‐activated kinase 1 (TAK1), an IκB kinase‐activating kinase, triggers the activation of NF‐κB. Th...

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Detalles Bibliográficos
Autores principales: Oura, Masahiro, Harada, Takeshi, Oda, Asuka, Teramachi, Jumpei, Nakayama, Atsushi, Sumitani, Ryohei, Inoue, Yusuke, Maeda, Yusaku, Sogabe, Kimiko, Maruhashi, Tomoko, Takahashi, Mamiko, Fujii, Shiro, Nakamura, Shingen, Miki, Hirokazu, Nakamura, Masafumi, Hara, Tomoyo, Yamagami, Hiroki, Kurahashi, Kiyoe, Endo, Itsuro, Hasegawa, Hiroo, Fujiwara, Hiroshi, Abe, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435715/
https://www.ncbi.nlm.nih.gov/pubmed/37601887
http://dx.doi.org/10.1002/jha2.758