Increased liver stiffness promotes hepatitis B progression by impairing innate immunity in CCl4-induced fibrotic HBV(+) transgenic mice

BACKGROUND: Hepatitis B virus (HBV) infection develops as an acute or chronic liver disease, which progresses from steatosis, hepatitis, and fibrosis to end-stage liver diseases such as cirrhosis and hepatocellular carcinoma (HCC). An increased stromal stiffness accompanies fibrosis in chronic liver...

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Detalles Bibliográficos
Autores principales: Bybee, Grace, Moeun, Youra, Wang, Weimin, Kharbanda, Kusum K., Poluektova, Larisa Y., Kidambi, Srivatsan, Osna, Natalia A., Ganesan, Murali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435739/
https://www.ncbi.nlm.nih.gov/pubmed/37600826
http://dx.doi.org/10.3389/fimmu.2023.1166171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435739/
https://www.ncbi.nlm.nih.gov/pubmed/37600826
http://dx.doi.org/10.3389/fimmu.2023.1166171

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