An HBV susceptibility variant of KNG1 modulates the therapeutic effects of interferons α and λ1 in HBV infection by promoting MAVS lysosomal degradation

BACKGROUND: Hepatitis B virus (HBV) infection is one of the main causes of hepatocellular carcinoma (HCC). The relationship between HBV infection and the host genome as well as their underlying mechanisms remain largely unknown. METHODS: In this study, we performed a whole-genome exon sequencing ana...

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Detalles Bibliográficos
Autores principales: Zhang, Bin, Han, Haijun, Zhao, Xinyi, Li, Andria N., Wang, Yan, Yuan, Wenji, Yang, Zhongli, Li, Ming D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435766/
https://www.ncbi.nlm.nih.gov/pubmed/37442062
http://dx.doi.org/10.1016/j.ebiom.2023.104694

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435766/
https://www.ncbi.nlm.nih.gov/pubmed/37442062
http://dx.doi.org/10.1016/j.ebiom.2023.104694

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