Cargando…

Fertility restoration in mice with chemotherapy induced ovarian failure using differentiated iPSCs

BACKGROUND: Treatment options for premature ovarian insufficiency (POI) are limited to hormone replacement and donor oocytes. A novel induced pluripotent stem cell (iPSC) transplant paradigm in a mouse model has potential translational applications for management of POI. METHODS: Mouse ovarian granu...

Descripción completa

Detalles Bibliográficos
Autores principales: Elias, Kevin M., Ng, Nicholas W., Dam, Kh U., Milne, Ankrish, Disler, Emily R., Gockley, Alison, Holub, Nicole, Seshan, Maya L., Church, George M., Ginsburg, Elizabeth S., Anchan, Raymond M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435842/
https://www.ncbi.nlm.nih.gov/pubmed/37482511
http://dx.doi.org/10.1016/j.ebiom.2023.104715