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Fertility restoration in mice with chemotherapy induced ovarian failure using differentiated iPSCs
BACKGROUND: Treatment options for premature ovarian insufficiency (POI) are limited to hormone replacement and donor oocytes. A novel induced pluripotent stem cell (iPSC) transplant paradigm in a mouse model has potential translational applications for management of POI. METHODS: Mouse ovarian granu...
Autores principales: | Elias, Kevin M., Ng, Nicholas W., Dam, Kh U., Milne, Ankrish, Disler, Emily R., Gockley, Alison, Holub, Nicole, Seshan, Maya L., Church, George M., Ginsburg, Elizabeth S., Anchan, Raymond M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435842/ https://www.ncbi.nlm.nih.gov/pubmed/37482511 http://dx.doi.org/10.1016/j.ebiom.2023.104715 |
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