Skeletal muscle cell protein dysregulation highlights the pathogenesis mechanism of myopathy-associated p97/VCP R155H mutations

p97/VCP, a hexametric member of the AAA-ATPase superfamily, has been associated with a wide range of cellular protein pathways, such as proteasomal degradation, the unfolding of polyubiquitinated proteins, and autophagosome maturation. Autosomal dominant p97/VCP mutations cause a rare hereditary mul...

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Detalles Bibliográficos
Autores principales: Luzzi, Anna, Wang, Feng, Li, Shan, Iacovino, Michelina, Chou, Tsui-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435852/
https://www.ncbi.nlm.nih.gov/pubmed/37602234
http://dx.doi.org/10.3389/fneur.2023.1211635

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435852/
https://www.ncbi.nlm.nih.gov/pubmed/37602234
http://dx.doi.org/10.3389/fneur.2023.1211635

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