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Antibodies to leukotoxin A from the periodontal pathogen Aggregatibacter actinomycetemcomitans in patients at an increased risk of rheumatoid arthritis

OBJECTIVES: Periodontitis and underlying bacteria have been linked to the development of rheumatoid arthritis (RA). One suggested pathogen is Aggregatibacter actinomycetemcomitans (A.a.), which expresses leukotoxin A (LtxA) that can citrullinate human proteins, providing a possible trigger for the p...

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Detalles Bibliográficos
Autores principales: Martinsson, Klara, Di Matteo, Andrea, Öhman, Carina, Johansson, Anders, Svärd, Anna, Mankia, Kulveer, Emery, Paul, Kastbom, Alf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10435988/
https://www.ncbi.nlm.nih.gov/pubmed/37601773
http://dx.doi.org/10.3389/fmed.2023.1176165