An attenuated herpesvirus vectored vaccine candidate induces T-cell responses against highly conserved porcine reproductive and respiratory syndrome virus M and NSP5 proteins that are unable to control infection

Porcine reproductive and respiratory syndrome virus (PRRSV) remains a leading cause of economic loss in pig farming worldwide. Existing commercial vaccines, all based on modified live or inactivated PRRSV, fail to provide effective immunity against the highly diverse circulating strains of both PRRS...

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Detalles Bibliográficos
Autores principales: de Brito, Rory C. F., Holtham, Kerry, Roser, Jessica, Saunders, Jack E., Wezel, Yvonne, Henderson, Summer, Mauch, Thekla, Sanz-Bernardo, Beatriz, Frossard, Jean-Pierre, Bernard, Matthieu, Lean, Fabian Z. X., Nunez, Alejandro, Gubbins, Simon, Suárez, Nicolás M., Davison, Andrew J., Francis, Michael J., Huether, Michael, Benchaoui, Hafid, Salt, Jeremy, Fowler, Veronica L., Jarvis, Michael A., Graham, Simon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436000/
https://www.ncbi.nlm.nih.gov/pubmed/37600784
http://dx.doi.org/10.3389/fimmu.2023.1201973

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436000/
https://www.ncbi.nlm.nih.gov/pubmed/37600784
http://dx.doi.org/10.3389/fimmu.2023.1201973

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