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An attenuated herpesvirus vectored vaccine candidate induces T-cell responses against highly conserved porcine reproductive and respiratory syndrome virus M and NSP5 proteins that are unable to control infection
Porcine reproductive and respiratory syndrome virus (PRRSV) remains a leading cause of economic loss in pig farming worldwide. Existing commercial vaccines, all based on modified live or inactivated PRRSV, fail to provide effective immunity against the highly diverse circulating strains of both PRRS...
Autores principales: | de Brito, Rory C. F., Holtham, Kerry, Roser, Jessica, Saunders, Jack E., Wezel, Yvonne, Henderson, Summer, Mauch, Thekla, Sanz-Bernardo, Beatriz, Frossard, Jean-Pierre, Bernard, Matthieu, Lean, Fabian Z. X., Nunez, Alejandro, Gubbins, Simon, Suárez, Nicolás M., Davison, Andrew J., Francis, Michael J., Huether, Michael, Benchaoui, Hafid, Salt, Jeremy, Fowler, Veronica L., Jarvis, Michael A., Graham, Simon P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436000/ https://www.ncbi.nlm.nih.gov/pubmed/37600784 http://dx.doi.org/10.3389/fimmu.2023.1201973 |
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