The protective effects of sesamol and/or the probiotic, Lactobacillus rhamnosus, against aluminum chloride-induced neurotoxicity and hepatotoxicity in rats: Modulation of Wnt/β-catenin/GSK-3β, JAK-2/STAT-3, PPAR-γ, inflammatory, and apoptotic pathways

Introduction: Aluminium (Al) is accumulated in the brain causing neurotoxicity and neurodegenerative disease like Alzheimer's disease (AD), multiple sclerosis, autism and epilepsy. Hence, attenuation of Al-induced neurotoxicity has become a “hot topic“ in looking for an intervention that slow d...

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Detalles Bibliográficos
Autores principales: Abu-Elfotuh, Karema, Selim, Heba Mohammed Refat M., Riad, Omnia Karem M., Hamdan, Ahmed M. E., Hassanin, Soha Osama, Sharif, Asmaa F., Moustafa, Nouran Magdy, Gowifel, Ayah M.H., Mohamed, Marwa Y. A., Atwa, Ahmed M., Zaghlool, Sameh S., El-Din, Mahmoud Nour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436218/
https://www.ncbi.nlm.nih.gov/pubmed/37601053
http://dx.doi.org/10.3389/fphar.2023.1208252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436218/
https://www.ncbi.nlm.nih.gov/pubmed/37601053
http://dx.doi.org/10.3389/fphar.2023.1208252

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