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The protective effects of sesamol and/or the probiotic, Lactobacillus rhamnosus, against aluminum chloride-induced neurotoxicity and hepatotoxicity in rats: Modulation of Wnt/β-catenin/GSK-3β, JAK-2/STAT-3, PPAR-γ, inflammatory, and apoptotic pathways
Introduction: Aluminium (Al) is accumulated in the brain causing neurotoxicity and neurodegenerative disease like Alzheimer's disease (AD), multiple sclerosis, autism and epilepsy. Hence, attenuation of Al-induced neurotoxicity has become a “hot topic“ in looking for an intervention that slow d...
Autores principales: | Abu-Elfotuh, Karema, Selim, Heba Mohammed Refat M., Riad, Omnia Karem M., Hamdan, Ahmed M. E., Hassanin, Soha Osama, Sharif, Asmaa F., Moustafa, Nouran Magdy, Gowifel, Ayah M.H., Mohamed, Marwa Y. A., Atwa, Ahmed M., Zaghlool, Sameh S., El-Din, Mahmoud Nour |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436218/ https://www.ncbi.nlm.nih.gov/pubmed/37601053 http://dx.doi.org/10.3389/fphar.2023.1208252 |
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