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Protocol for human brain organoid transplantation into a rat visual cortex to model neural repair

Human stem-cell-derived organoids represent a promising substrate for transplantation-based neural repair. Here, we describe a protocol for transplanting forebrain organoids into an injured adult rat visual cortex. This protocol includes surgical details for craniectomy, aspiration injury, organoid...

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Detalles Bibliográficos
Autores principales: Jgamadze, Dennis, Harary, Paul M., Castellanos, Mackenzie, Blue, Rachel, Song, Hongjun, Ming, Guo-li, Chen, H. Isaac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436235/
https://www.ncbi.nlm.nih.gov/pubmed/37585295
http://dx.doi.org/10.1016/j.xpro.2023.102470