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Chemical Tools to Image the Activity of PAR-Cleaving Proteases

[Image: see text] Protease-activated receptors (PARs) comprise a family of four G protein-coupled receptors (GPCRs) that have broad functions in health and disease. Unlike most GPCRs, PARs are uniquely activated by proteolytic cleavage of their extracellular N termini. To fully understand PAR activa...

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Detalles Bibliográficos
Autores principales: Lee, Irene Y., Tantisirivat, Piyapa, Edgington-Mitchell, Laura E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436261/
https://www.ncbi.nlm.nih.gov/pubmed/37599791
http://dx.doi.org/10.1021/acsbiomedchemau.3c00019