Cargando…

Chemical Tools to Image the Activity of PAR-Cleaving Proteases

[Image: see text] Protease-activated receptors (PARs) comprise a family of four G protein-coupled receptors (GPCRs) that have broad functions in health and disease. Unlike most GPCRs, PARs are uniquely activated by proteolytic cleavage of their extracellular N termini. To fully understand PAR activa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Irene Y., Tantisirivat, Piyapa, Edgington-Mitchell, Laura E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436261/ https://www.ncbi.nlm.nih.gov/pubmed/37599791 http://dx.doi.org/10.1021/acsbiomedchemau.3c00019

Ejemplares similares

Comparative Assessment of Substrates and Activity Based Probes as Tools for Non-Invasive Optical Imaging of Cysteine Protease Activity
por: Blum, Galia, et al.
Publicado: (2009)

Novel broad-spectrum activity-based probes to profile malarial cysteine proteases
por: Tan, Michele S. Y., et al.
Publicado: (2020)

Humanizing the Protease-Activated Receptor (PAR) Expression Profile in Mouse Platelets by Knocking PAR1 into the Par3 Locus Reveals PAR1 Expression Is Not Tolerated in Mouse Platelets
por: French, Shauna L., et al.
Publicado: (2016)

Human osteoarthritis knee joint synovial fluids cleave and activate Proteinase-Activated Receptor (PAR) mediated signaling
por: Chandrabalan, Arundhasa, et al.
Publicado: (2023)

Correction: Novel broad-spectrum activity-based probes to profile malarial cysteine proteases
por: Tan, Michele S. Y., et al.
Publicado: (2020)

Intramembrane cleaving proteases (I-CLiPs) as guardians of shuttling proteins
por: Fluhrer, Regina
Publicado: (2014)

Botulinum protease-cleaved SNARE fragments induce cytotoxicity in neuroblastoma cells
por: Arsenault, Jason, et al.
Publicado: (2014)

Protease-activated receptor (PAR)-2 is required for PAR-1 signalling in pulmonary fibrosis
por: Lin, Cong, et al.
Publicado: (2015)

Post-translational regulation of the cleaved fragment of Par-4 in ovarian and endometrial cancer cells
por: Brasseur, Kevin, et al.
Publicado: (2016)

Structure of protease-cleaved Escherichia coli α-2-macroglobulin reveals a putative mechanism of conformational activation for protease entrapment
por: Fyfe, Cameron D., et al.
Publicado: (2015)

Von Willebrand Factor-Cleaving Protease Activity in Thrombotic Microangiopathy: First Report From Iran
por: Ardalan, Mohammadreza, et al.
Publicado: (2014)

Human Rhinovirus 3C protease cleaves RIPK1, concurrent with caspase 8 activation
por: Croft, Sarah N., et al.
Publicado: (2018)

Astacin Proteases Cleave Dentin Sialophosphoprotein (Dspp) to Generate Dentin Phosphoprotein (Dpp)
por: Tsuchiya, Shuhei, et al.
Publicado: (2011)

In Silico Prediction of Mutant HIV-1 Proteases Cleaving a Target Sequence
por: Jensen, Jan H., et al.
Publicado: (2014)

Both Full-Length and Protease-Cleaved Products of Osteopontin Are Elevated in Infectious Diseases
por: Hattori, Toshio, et al.
Publicado: (2021)

The papain-like protease of coronaviruses cleaves ULK1 to disrupt host autophagy
por: Mohamud, Yasir, et al.
Publicado: (2021)

CHEMICALLY CLEAVED GRAPHITE SUPPORT FILMS FOR ELECTRON MICROSCOPY
por: Dobelle, William H., et al.
Publicado: (1968)

Platelet-derived calpain cleaves the endothelial protease-activated receptor 1 to induce vascular inflammation in diabetes
por: Kyselova, Anastasia, et al.
Publicado: (2020)

TRAF3IP3 Is Cleaved by EV71 3C Protease and Exhibits Antiviral Activity
por: Li, Hui, et al.
Publicado: (2022)

SPRTN protease-cleaved MRE11 decreases DNA repair and radiosensitises cancer cells
por: Na, Juri, et al.
Publicado: (2021)

Chemical Tools and Biochemical Assays for SUMO Specific Proteases (SENPs)
por: Jia, Yuqing, et al.
Publicado: (2019)

Protease-activated receptors (PARs): mechanisms of action and potential therapeutic modulators in PAR-driven inflammatory diseases
por: Heuberger, Dorothea M., et al.
Publicado: (2019)

Posttranslational processing of the prohormone-cleaving Kex2 protease in the Saccharomyces cerevisiae secretory pathway
Publicado: (1991)

TagA is a secreted protease of Vibrio cholerae that specifically cleaves mucin glycoproteins
por: Szabady, Rose L., et al.
Publicado: (2011)

Enterohaemorrhagic Escherichia coli haemolysin is cleaved and inactivated by serine protease EspPα
por: Brockmeyer, Jens, et al.
Publicado: (2011)

Unc93b Induces Apoptotic Cell Death and Is Cleaved by Host and Enteroviral Proteases
por: Harris, Katharine G., et al.
Publicado: (2015)

HIV-1 protease cleaves the serine-threonine kinases RIPK1 and RIPK2
por: Wagner, Roland N., et al.
Publicado: (2015)

A human endogenous retrovirus encoded protease potentially cleaves numerous cellular proteins
por: Rigogliuso, Giuseppe, et al.
Publicado: (2019)

Histone 2B Facilitates Plasminogen-Enhanced Endothelial Migration through Protease-Activated Receptor 1 (PAR1) and Protease-Activated Receptor 2 (PAR2)
por: Das, Mitali, et al.
Publicado: (2022)

Correction to: protease-activated receptors (PARs): mechanisms of action and potential therapeutic modulators in PAR-driven inflammatory diseases
por: Heuberger, Dorothea M., et al.
Publicado: (2019)

Protease-activated receptors (PARs)—biology and role in cancer invasion and metastasis
por: Wojtukiewicz, Marek Z., et al.
Publicado: (2015)

Role of protease‐activated receptor‐1 (PAR‐1) in the glomerular filtration barrier integrity
por: Medipally, Ajay, et al.
Publicado: (2022)

Streptococcal SpeB Cleaved PAR-1 Suppresses ERK Phosphorylation and Blunts Thrombin-Induced Platelet Aggregation
por: Ender, Miriam, et al.
Publicado: (2013)

Ovastacin, a cortical granule protease, cleaves ZP2 in the zona pellucida to prevent polyspermy
por: Burkart, Anna D., et al.
Publicado: (2012)

Innate immune sensor LGP2 is cleaved by the Leader protease of foot-and-mouth disease virus
por: Rodríguez Pulido, Miguel, et al.
Publicado: (2018)

Campylobacter jejuni Serine Protease HtrA Cleaves the Tight Junction Component Claudin-8
por: Sharafutdinov, Irshad, et al.
Publicado: (2020)

Hepatitis C Virus NS3/4A Protease Inhibits Complement Activation by Cleaving Complement Component 4
por: Mawatari, Seiichi, et al.
Publicado: (2013)

The Nuclear Inclusion a (NIa) Protease of Turnip Mosaic Virus (TuMV) Cleaves Amyloid-β
por: Han, Hye-Eun, et al.
Publicado: (2010)

Complement factor C4a does not activate protease‐activated receptor 1 (PAR1) or PAR4 on human platelets
por: Han, Xu, et al.
Publicado: (2020)

Emerging Roles of Protease-Activated Receptors (PARs) in the Modulation of Synaptic Transmission and Plasticity
por: Price, Rachel, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hiqn1madb6bhts7ctqk3pmr3h4