X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences

[Image: see text] The rational design of small molecules that target specific DNA sequences is a promising strategy to modulate gene expression. This report focuses on a diamidinobenzimidazole compound, whose selective binding to the minor groove of AT DNA sequences holds broad significance in the m...

Descripción completa

Detalles Bibliográficos
Autores principales: Ogbonna, Edwin N., Paul, Ananya, Farahat, Abdelbasset A., Terrell, J. Ross, Mineva, Ekaterina, Ogbonna, Victor, Boykin, David W, Wilson, W. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436263/
https://www.ncbi.nlm.nih.gov/pubmed/37599788
http://dx.doi.org/10.1021/acsbiomedchemau.3c00002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436263/
https://www.ncbi.nlm.nih.gov/pubmed/37599788
http://dx.doi.org/10.1021/acsbiomedchemau.3c00002

Ejemplares similares