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X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences

[Image: see text] The rational design of small molecules that target specific DNA sequences is a promising strategy to modulate gene expression. This report focuses on a diamidinobenzimidazole compound, whose selective binding to the minor groove of AT DNA sequences holds broad significance in the m...

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Detalles Bibliográficos
Autores principales:	Ogbonna, Edwin N., Paul, Ananya, Farahat, Abdelbasset A., Terrell, J. Ross, Mineva, Ekaterina, Ogbonna, Victor, Boykin, David W, Wilson, W. David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436263/ https://www.ncbi.nlm.nih.gov/pubmed/37599788 http://dx.doi.org/10.1021/acsbiomedchemau.3c00002

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