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Rapid Chemical Ligation of DNA and Acyclic Threoninol Nucleic Acid (aTNA) for Effective Nonenzymatic Primer Extension
[Image: see text] Previously, nonenzymatic primer extension reaction of acyclicl-threoninol nucleic acid (L-aTNA) was achieved in the presence of N-cyanoimidazole (CNIm) and Mn(2+); however, the reaction conditions were not optimized and a mechanistic insight was not sufficient. Herein, we report in...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436273/ https://www.ncbi.nlm.nih.gov/pubmed/37466125 http://dx.doi.org/10.1021/jacs.3c04979 |