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Rutaecarpine induces the differentiation of triple-negative breast cancer cells through inhibiting fumarate hydratase
BACKGROUND: Triple-negative breast cancer (TNBC) is one of the most aggressive human cancers and has poor prognosis. Approximately 80% of TNBC cases belong to the molecular basal-like subtype, which can be exploited therapeutically by inducing differentiation. However, the strategies for inducing th...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436383/ https://www.ncbi.nlm.nih.gov/pubmed/37592347 http://dx.doi.org/10.1186/s12967-023-04396-w |