Rutaecarpine induces the differentiation of triple-negative breast cancer cells through inhibiting fumarate hydratase

BACKGROUND: Triple-negative breast cancer (TNBC) is one of the most aggressive human cancers and has poor prognosis. Approximately 80% of TNBC cases belong to the molecular basal-like subtype, which can be exploited therapeutically by inducing differentiation. However, the strategies for inducing th...

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Detalles Bibliográficos
Autores principales: Lei, Jie, Pan, Yujia, Gao, Rui, He, Bin, Wang, Zifeng, Lei, Xinxing, Zhang, Zijian, Yang, Na, Yan, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436383/
https://www.ncbi.nlm.nih.gov/pubmed/37592347
http://dx.doi.org/10.1186/s12967-023-04396-w

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