The tyrosine kinase inhibitor Dasatinib reduces cardiac steatosis and fibrosis in obese, type 2 diabetic mice

BACKGROUND: Cardiac steatosis is an early yet overlooked feature of diabetic cardiomyopathy. There is no available therapy to treat this condition. Tyrosine kinase inhibitors (TKIs) are used as first or second-line therapy in different types of cancer. In cancer patients with diabetes mellitus, TKIs...

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Detalles Bibliográficos
Autores principales: Gu, Yue, Avolio, Elisa, Alvino, Valeria V, Thomas, Anita C, Herman, Andrew, Miller, Poppy J, Sullivan, Niall, Faulkner, Ashton, Madeddu, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436421/
https://www.ncbi.nlm.nih.gov/pubmed/37592236
http://dx.doi.org/10.1186/s12933-023-01955-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436421/
https://www.ncbi.nlm.nih.gov/pubmed/37592236
http://dx.doi.org/10.1186/s12933-023-01955-9

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