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Dynamic alterations in metabolomics and transcriptomics associated with intestinal fibrosis in a 2,4,6-trinitrobenzene sulfonic acid-induced murine model

BACKGROUND & AIMS: Intestinal fibrosis is a common and severe complication of inflammatory bowel disease without clear pathogenesis. Abnormal expression of host genes and metabolic perturbations might associate with the onset of intestinal fibrosis. In this study, we aimed to investigate the rel...

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Detalles Bibliográficos
Autores principales: Wu, Jinzhen, Tian, Zhenyi, Zhuang, Xiaoduan, Chen, Yiru, Fan, Tingting, Li, Jiayun, Wang, Xinying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436422/
https://www.ncbi.nlm.nih.gov/pubmed/37592304
http://dx.doi.org/10.1186/s12967-023-04392-0