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Dynamic alterations in metabolomics and transcriptomics associated with intestinal fibrosis in a 2,4,6-trinitrobenzene sulfonic acid-induced murine model
BACKGROUND & AIMS: Intestinal fibrosis is a common and severe complication of inflammatory bowel disease without clear pathogenesis. Abnormal expression of host genes and metabolic perturbations might associate with the onset of intestinal fibrosis. In this study, we aimed to investigate the rel...
Autores principales: | Wu, Jinzhen, Tian, Zhenyi, Zhuang, Xiaoduan, Chen, Yiru, Fan, Tingting, Li, Jiayun, Wang, Xinying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436422/ https://www.ncbi.nlm.nih.gov/pubmed/37592304 http://dx.doi.org/10.1186/s12967-023-04392-0 |
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