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Heterologous production of the insecticidal pea seed albumin PA1 protein by Pichia pastoris and protein engineering to potentiate aphicidal activity via fusion to snowdrop lectin Galanthus nivalis agglutinin; GNA)

BACKGROUND: New bioinsecticides with novel modes of action are urgently needed to minimise the environmental and safety hazards associated with the use of synthetic chemical pesticides and to combat growing levels of pesticide resistance. The pea seed albumin PA1b knottin peptide is the only known p...

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Detalles Bibliográficos
Autores principales: De-Thier, Jake S., Pyati, Prashant, Bell, Jack, Readshaw, Jennifer J., Brown, Adrian P., Fitches, Elaine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436433/
https://www.ncbi.nlm.nih.gov/pubmed/37592258
http://dx.doi.org/10.1186/s12934-023-02176-1