Breast cancer patient-derived microtumors resemble tumor heterogeneity and enable protein-based stratification and functional validation of individualized drug treatment

Despite tremendous progress in deciphering breast cancer at the genomic level, the pronounced intra- and intertumoral heterogeneity remains a major obstacle to the advancement of novel and more effective treatment approaches. Frequent treatment failure and the development of treatment resistance hig...

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Detalles Bibliográficos
Autores principales: Anderle, Nicole, Schäfer-Ruoff, Felix, Staebler, Annette, Kersten, Nicolas, Koch, André, Önder, Cansu, Keller, Anna-Lena, Liebscher, Simone, Hartkopf, Andreas, Hahn, Markus, Templin, Markus, Brucker, Sara Y., Schenke-Layland, Katja, Schmees, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436441/
https://www.ncbi.nlm.nih.gov/pubmed/37596623
http://dx.doi.org/10.1186/s13046-023-02782-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436441/
https://www.ncbi.nlm.nih.gov/pubmed/37596623
http://dx.doi.org/10.1186/s13046-023-02782-2

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