Methylation is maintained specifically at imprinting control regions but not other DMRs associated with imprinted genes in mice bearing a mutation in the Dnmt1 intrinsically disordered domain

Differential methylation of imprinting control regions in mammals is essential for distinguishing the parental alleles from each other and regulating their expression accordingly. To ensure parent of origin-specific expression of imprinted genes and thereby normal developmental progression, the diff...

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Detalles Bibliográficos
Autores principales: Regmi, Shaili, Giha, Lana, Ali, Ahado, Siebels-Lindquist, Christine, Davis, Tamara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436486/
https://www.ncbi.nlm.nih.gov/pubmed/37601113
http://dx.doi.org/10.3389/fcell.2023.1192789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436486/
https://www.ncbi.nlm.nih.gov/pubmed/37601113
http://dx.doi.org/10.3389/fcell.2023.1192789

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