Unveiling the antitumor potential of novel N-(substituted-phenyl)-8-methoxycoumarin-3-carboxamides as dual inhibitors of VEGFR2 kinase and cytochrome P450 for targeted treatment of hepatocellular carcinoma

Being the sixth most diagnosed cancer and the fourth leading cause of cancer-related deaths worldwide, liver cancer is considered as a serious disease with a high prevalence and poor prognosis. Current anticancer drugs for liver cancer have drawbacks, such as limited efficacy in later stages of the...

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Detalles Bibliográficos
Autores principales: Radwan, Eman M., Abo-Elabass, Eman, Abd El-Baky, Atef E., Alshwyeh, Hussah Abdullah, Almaimani, Riyad A., Almaimani, Ghassan, Ibrahim, Ibrahim Abdel Aziz, Albogami, Abdulaziz, Jaremko, Mariusz, Alshawwa, Samar Z., Saied, Essa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436493/
https://www.ncbi.nlm.nih.gov/pubmed/37601910
http://dx.doi.org/10.3389/fchem.2023.1231030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436493/
https://www.ncbi.nlm.nih.gov/pubmed/37601910
http://dx.doi.org/10.3389/fchem.2023.1231030

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