The tight junction protein claudin 6 is a potential target for patient-individualized treatment in esophageal and gastric adenocarcinoma and is associated with poor prognosis

BACKGROUND: The prognosis of esophageal adenocarcinoma (EAC) and gastric adenocarcinoma (GAC) remains poor, and new therapeutic approaches are urgently needed. Claudin 6 (CLDN6) is an oncofetal antigen that is largely absent in healthy tissues and upregulated in several cancers, making it a promisin...

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Detalles Bibliográficos
Autores principales: Simon, Adrian Georg, Lyu, Su Ir, Laible, Mark, Wöll, Stefan, Türeci, Özlem, Şahin, Uğur, Alakus, Hakan, Fahrig, Luca, Zander, Thomas, Buettner, Reinhard, Bruns, Christiane Josephine, Schroeder, Wolfgang, Gebauer, Florian, Quaas, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436499/
https://www.ncbi.nlm.nih.gov/pubmed/37592303
http://dx.doi.org/10.1186/s12967-023-04433-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436499/
https://www.ncbi.nlm.nih.gov/pubmed/37592303
http://dx.doi.org/10.1186/s12967-023-04433-8

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