Age-adjusted high-dose chemotherapy followed by autologous stem cell transplantation or conventional chemotherapy with R-MP as first-line treatment in elderly primary CNS lymphoma patients – the randomized phase III PRIMA-CNS trial

BACKGROUND: Older primary central nervous system lymphoma (PCNSL) patients have an inferior prognosis compared to younger patients because available evidence on best treatment is scarce and treatment delivery is challenging due to comorbidities and reduced performance status. High-dose chemotherapy...

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Detalles Bibliográficos
Autores principales: Isbell, Lisa K, Uibeleisen, Roswitha, Friedl, Alexander, Burger, Elvira, Dopatka, Tatja, Scherer, Florian, Orban, Andras, Lauer, Eliza, Malenica, Natalie, Semenova, Inna, Vreden, Annika, Valk, Elke, Wendler, Julia, Neumaier, Simone, Fricker, Heidi, El Rabih, Abed Al Hadi, Gloggengießer, Cora, Hilbig, Daniela, Bleul, Sabine, Weis, Joachim, Gmehlin, Dennis, Backenstrass, Matthias, Wirtz, Sebastian, Ihorst, Gabriele, Finke, Jürgen, Illerhaus, Gerald, Schorb, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436648/
https://www.ncbi.nlm.nih.gov/pubmed/37596517
http://dx.doi.org/10.1186/s12885-023-11193-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10436648/
https://www.ncbi.nlm.nih.gov/pubmed/37596517
http://dx.doi.org/10.1186/s12885-023-11193-7

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